Targeted Results,
Delivered Directly.
Skin Mesotherapy — What Creams Cannot Reach.
Two precision treatments — a multi-pathway whitening cocktail for melasma and pigmentation, and a fat lysis solution for double chin and body contouring. Both bypass the skin barrier entirely to deliver results at therapeutic concentrations.
6-Pathway
Melanin blocking formula
Permanent Results
Fat cells destroyed, not shrunk
Why Mesotherapy Outperforms
Topical Products Alone
Even the most potent brightening or fat-dissolving ingredients face one insurmountable limitation when applied to the skin surface: the stratum corneum barrier. Mesotherapy bypasses it entirely.
Faster Onset
Results visible from 2–4 weeks vs. 4–12 weeks with topical products
Higher Concentration
Active ingredients delivered at therapeutic concentrations directly at the target site
Precise Targeting
Only the treated area is affected — no systemic side effects from localized delivery
Superior Results
Results impossible to achieve with skincare alone — proven in peer-reviewed clinical trials
| Delivery Route | Skin Penetration | Target Concentration | Onset | Downtime |
|---|---|---|---|---|
| Topical Cream | Limited (barrier blocks) | Low at dermis | 4–12 weeks | None |
| Oral (Systemic) | Good (systemic) | Systemic effect | 4–8 weeks | None |
| Mesotherapy ★ | Direct intradermal | High at target | 2–4 weeks | Minimal |
Whitening Cocktail —
Stop Melasma at Its Source
What It Treats
A dermatologist-formulated cocktail delivered directly into the dermis — targeting multiple melanin production pathways simultaneously. Superior to topical brightening agents because it delivers active ingredients where melanocytes actually live.
Treatment Protocol
Clinical Evidence
- Significantly reduces Modified MASI scores vs. baseline
- Glutathione-containing cocktail proves superior to Tranexamic acid alone
- Safe and effective across Fitzpatrick skin types III–VI
- Best results when combined with topical maintenance + SPF
The 6-Pathway Formula
Each ingredient targets a different step in the melanin production cycle
Tranexamic Acid
4 mg/mLBlocks UV-induced plasminogen pathway — cuts off the signal that triggers melanin overproduction.
Vitamin C
3% L-Ascorbic AcidInhibits tyrosinase — the rate-limiting enzyme in melanin production. Powerful antioxidant and collagen booster.
Glutathione
2% — Superior FormulaSwitches melanin from dark eumelanin to lighter pheomelanin — a unique brightening mechanism no topical can replicate.
Kojic Acid
Tyrosinase InhibitorChelates copper ions essential for tyrosinase activity — an extra layer of melanin enzyme inhibition alongside Vitamin C.
Niacinamide
Transfer BlockerPrevents melanin packets from transferring to surface skin cells — stops pigmentation at the final step before it shows.
Arbutin
Gentle & Sensitive-SafeGentle hydroquinone derivative — inhibits tyrosinase without irritation, ideal for sensitive and post-inflammatory skin.
6 active brightening ingredients. 1 dermatologist-precision formula.
Whitening Cocktail — Before & After
Individual results may vary. Course of 6 sessions over 3 months.
Fat Lysis Solution —
Dissolve the Double Chin
A non-surgical injectable treatment using phosphatidylcholine (PC) and deoxycholic acid (DC) to permanently dissolve localized fat cells. The same active mechanism as FDA-approved Kybella® — applied by an expert dermatologist to face and body areas. Fat cells are destroyed, not just shrunk.
How It Works — 4 Steps to Permanent Fat Reduction
Injection into Fat Layer
PC + DC solution injected in a grid pattern directly into the subcutaneous fat deposit.
Cell Membrane Disruption
Deoxycholic acid disrupts the phospholipid bilayer of fat cell membranes — initiating controlled apoptosis (cell death).
Natural Clearance
Macrophages phagocytose the destroyed fat debris. Fatty acids enter lymphatic and circulatory system for metabolic elimination.
Permanent Result
Treated fat cells do not regenerate. Unlike diet or exercise that shrink fat cells, fat lysis permanently eliminates them from the treated area.
Results Timeline
Treatment Areas
Face
- Double chin (most popular)
- Jowl & lower face fat
- Buccal fat (facial fullness)
- Pre-auricular area
Body
- Flanks & love handles
- Abdominal fat
- Bra fat / back rolls
- Inner thighs & upper arms
Fat Lysis vs. Liposuction
| Fat Lysis | Liposuction | |
|---|---|---|
| Anesthesia | Topical only | General / IV sedation |
| Incisions | None | Small cuts |
| Downtime | 3–5 days | 1–2 weeks |
| Risk Profile | Minimal | Surgical risks |
| Best for | Small localized fat | Large volume fat |
Ideal Candidates
- Stubborn localized fat that doesn't respond to diet & exercise
- Seeking a non-surgical option before considering liposuction
- Realistic expectations about a gradual weeks-to-months timeline
- Not suitable: pregnancy, liver/kidney conditions, clotting disorders
Fat Lysis — Before & After
Individual results may vary. Course of 3–5 sessions, 4 weeks apart.
Maximize Your Results
Dr. Pang designs comprehensive protocols that combine mesotherapy with complementary treatments for superior and longer-lasting outcomes.
Optimal Melasma Protocol
Enhanced Fat Reduction Protocol
Dr. Gateorn Pongarnar
Board-Certified Dermatologist
Dr. Pang formulates and administers every mesotherapy treatment personally — selecting ingredient combinations based on your individual skin analysis, Fitzpatrick skin type, and treatment history. No generic protocols.
Both whitening cocktail and fat lysis formulas used at Dr. Pang Skin Clinic are backed by published clinical evidence. Technique precision is critical — especially for fat lysis, where grid depth and dosing directly determine both safety and outcome.
Real Results from Real Patients
From melasma improvement to double chin reduction — hear from patients who've experienced mesotherapy at Dr. Pang Skin Clinic.
Frequently Asked Questions
Everything you need to know about whitening cocktail and fat lysis mesotherapy at Dr. Pang Skin Clinic.
For moderate-to-severe melasma, yes — topical products face penetration limitations that mesotherapy bypasses entirely. Mesotherapy delivers active ingredients at therapeutic concentrations directly into the dermis where melanocytes reside. Topical products remain important for maintenance between sessions — the optimal approach combines both.
Most patients notice improved skin radiance and early pigmentation reduction by sessions 2–3 (4–6 weeks). Significant, measurable MASI (Melasma Area and Severity Index) score reduction is typically documented at the 12-week mark after completing 6 sessions. Results continue to improve with maintenance sessions.
Yes — deoxycholic acid permanently destroys the treated fat cells. Unlike diet and exercise that shrink fat cells, fat lysis eliminates them entirely. The treated fat does not return. However, remaining untreated fat cells elsewhere can still expand with significant weight gain, so maintaining a stable weight protects and prolongs results.
A burning or stinging sensation is typical during injection. Numbing cream is applied 30 minutes beforehand to minimize discomfort. Afterward: swelling, warmth, and heaviness in the treated area for 3–5 days — this is the normal inflammatory response as fat cells are destroyed. Temporary hardness (nodulation) may occur days 3–7 and resolves on its own. Most patients find the experience manageable and return to normal activities.
Most patients see optimal double chin reduction after 3 sessions, spaced 4–6 weeks apart. Patients with larger fat deposits may require 4–5 sessions for full correction. Clinical studies show 74.5–86.5% of patients achieve satisfactory, smooth results after completing the treatment course.
Yes — mesotherapy and laser treatments are highly complementary for melasma. Dr. Pang recommends picosecond or Q-switched laser every 6–8 weeks alongside monthly whitening mesotherapy sessions for comprehensive pigmentation management. The mesotherapy also accelerates recovery after laser treatments by delivering healing nutrients directly into the skin.
Both treatments are not recommended during pregnancy or breastfeeding, or for patients with active skin infections at the treatment site. For fat lysis specifically: liver or kidney conditions and clotting disorders are contraindications. Patients on blood thinners should inform Dr. Pang before treatment. A thorough consultation and medical history review is conducted before any mesotherapy procedure.
Whitening cocktail: minimal — micro-papule injection marks resolve within hours; mild redness clears in 1–4 hours. Most patients return to work and social activities the same day. Fat lysis: mild swelling, warmth, and heaviness for 3–5 days (similar to a mild bruise in the treated area). Most daily activities can continue, but avoid strenuous exercise for 3–5 days. No makeup on treated face areas for 6–8 hours.
Ready for Results That Go Deeper?
Book a consultation with Dr. Pang — she'll assess your skin, identify the right treatment (or combination), and build a protocol that delivers real, measurable results.
No commitment required at consultation. Treatments are recommended only after thorough assessment.